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Whole Herbs or Standardized Plant Constituents? PDF Print E-mail
by Linda Page, N.D., Ph.D.
Whole Herbs or Standardized Plant Constituents?
Vol 23 #4 2001

What is sacrificed when herbal constituents are “standardized”? This question is important as more and more Americans are increasing their use of herbs while standardized separate herbal constituents are becoming popular as herbal manufacturers enter drug-oriented health care markets. Standardization is seen by some companies, especially those whose main focus has been vitamins or other partitioned supplements such as amino acids, as a way for herb products to challenge the mainstream drug company monopoly, by measuring and assuring an “active constituent” of a plant for medicinal use. Standardization is also considered as a way to deal with FDA regulations that require drug measurability and FDA guidelines that require so-called “active” ingredients to be stated on product labels. As herb companies begin to educate the public about the health benefits of herbs, a way must be found to work with regulations that were never intended to deal with the complexities or broad-based effects of herbal healing.

Standardization attempts to isolate “active constituents” for a very limited function. Standardization procedures also allow the use of substandard materials. Since only one “active constituent” is measured, that constituent may be boosted with a concentration of an isolated element to reach the required standard, regardless of the quality of the herb itself. No one constituent, no matter how worthwhile, can do its healing job without the right stuff from the rest of the herb. For example, ginseng has become a popular ingredient in many herbal products. One laboratory test identified two of its 22 known constituents (called Rb1 and Rb2) in an attempt to isolate ginseng’s functions as an antioxidant and for lowering cholesterol. Yet thousands of years of worldwide, well-documented experience shows that ginseng has dozens of other actions that control disease and promote wellness—functions entirely missed by this test. Should we deny people the ultimate value and effectiveness of ginseng’s activity simply because a laboratory hasn’t tested for every one of its functions yet?

WHOLE HERB HEALING
As a naturopath and traditional herbalist I believe that standardization shortchanges the full spectrum of whole herb healing. Throughout the ages, from all cultures and traditions, healers have effectively used whole herbs for whole bodies with success that rivals modern-day allopathic medicine. As naturally concentrated foods, herbs have the unique ability to address a multiplicity of problems simultaneously.

In most cases, the full medicinal value of herbs is in their internal complexity. Single herbs contain dozens of natural chemical constituents working synergistically. That is why an herb is rarely ever known for just a single function. The evolutionary development of each herb has created a whole essence: the natural herb in correct and balanced rations with all its constituents. Many of these constituents within a whole herb are unknown—even to modern science—and internal chemical reactions within and among herbs are even less understood. I believe that a combination of herbal nutrients best encourages overall body balance. Since all body parts and most disease symptoms are interrelated, it is wise to use a compound of herbs which can affect each part of the problem. Also, used in their whole form, herbs, like foods, nourish the body with little danger of toxicity.

Potentiating herbal formulas to reach certain standardized constituents makes them more druglike, without the protection of their natural gentleness and balance. For example, recent studies show that the standardized compound, hypericin, found in St.-John’s-wort, is a strong inhibitor of monoamine oxidase (MAO) and that Prozac™ should never be taken with MAO antidepressants. Herbs have rejuvenative qualities entirely missed by standardization. No lab test can begin to quantify all that whole natural plants have to offer us. Standardizing potency for only one or two extracted “active ingredients” for certain vested interests, attempts to use limited laboratory procedures to convince the AMA, the FDA and medical scientists of the value of herbal therapy. Yet quality and consistency are a major concern in ascertaining herbal effectiveness.

Somehow herbalists and herbal product suppliers must integrate herbal traditions, ethical commitment, FDA regulations and consumer concerns. We can’t let ourselves forget that the activity of herbs is due not only to their biochemical properties but also to their unique, holistic effects and most importantly, to their interactions with the human body.

And we must not fall into the same wrong-headed, self-defeating pit that occurred 40 years ago when the regulations for standardization of drugs nearly killed all herbal medicine.
 
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