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Obesity, Weight Loss and Glucose Control


Chromium Picolinate
Getting to the heart of insulin resistance
by James J. Gormley

Chromium is a trace mineral required by our body’s master metabolic hormone, insulin. Since the body can’t manufacture this mineral, we have to obtain it through diet or supplementation to achieve healthy blood sugar and cholesterol levels. Unfortunately, chromium isn’t found in optimal amounts in foods; whatever is there is compromised by modern food processing and cooking at high temperatures.

In fact, in 1985 Richard A. Anderson, Ph.D., reported that not getting optimal chromium from foods is common in the U.S. In addition, nutritional chromium isn’t well absorbed from the diet. Even worse, high fiber diets and certain medications (such as aspirin and antacids) further interfere with chromium absorption; even aging itself is associated with a 25 to 40 percent drop in body levels of chromium.

The branded ingredient, Chromax® chromium picolinate, is considered by experts to be better absorbed and more usable by the body than other forms of chromium. In a 1998 review, Dr. Anderson wrote: “Essentially all the studies employing the more bioavailable chromium picolinate have reported positive effects, with greater effects reported at 1,000 mcg/day than at 200 mcg/day.”

The insulin resistance story
According to the American Association of Endocrinologists (AACE), Syndrome X, also known as metabolic syndrome, is an epidemic condition that affects one in three Americans nearly 95 million people. The number of people with insulin resistance has skyrocketed 61 percent in the last decade.

Syndrome X is a metabolic disorder that underlies some of the most serious, chronic and costly diseases in the U.S. It is a constellation of metabolic disorders brought on by insulin resistance. Symptoms include obesity, high cholesterol and triglycerides, hypertension, and poor use of blood sugar (or glucose intolerance).

Although most people with insulin resistance can, in the early stages, usually produce enough insulin to mask obvious symptoms of poor insulin and glucose control, some will eventually develop type II diabetes. The majority of these people, however, are still at a significantly increased risk for heart attack, stroke and other diseases.

How chromium fits in
Research has shown that diets low in chromium negatively affect glucose tolerance and insulin in those who already have mildly impaired glucose tolerance. It has been suggested that large losses of chromium over time may contribute to insulin resistance and exacerbate already compromised chromium status in people with type II diabetes. Studies have found that chromium supplementation improves insulin sensitivity. Of 12 human studies looking at chromium’s effectiveness in improving glucose metabolism, 11 show significant positive effects. These studies suggest supplementation with 200 to 1,000 mcg of chromium a day because chromium picolinate improves glucose tolerance and circulating insulin levels.

In a study of 162 patients, supplementation with 200 mcg of chromium a day resulted in the reduced need for insulin and glucose-lowering medications in 118 of the patients. Two six-week, double-blind studies found that supplements of 200 mcg of chromium a day resulted in significant decreases in fasting blood sugar and levels of glycosylated hemoglobin.

An eight-month study of 29 people found that supplementing with 1,000 mcg per day of chromium picolinate significantly improved insulin sensitivity. Chromium picolinate supplements have also been found to improve glucose tolerance and lower insulin levels in women with gestational diabetes.

Getting to the heart of insulin resistance and all of the health conditions touched by it must involve both nutrition and exercise. Research has shown that supplementing with Chromax chromium picolinate is a critical part of a wholebody approach to health, one which truly helps us get to the very metabolic core of Syndrome X.
 
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