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Pycnogenol®, Nature’s Super Antioxidant, Fighting Inflammation

by Frank Schönlau, Ph.D.

The health community is paying more and more attention to inflammation in the body and the possible long-term consequences on an individual’s health if not treated properly. Years ago, if a patient developed swelling or inflammation, it was treated depending on the level of discomfort. Many people didn’t even bother going to the doctor if the symptoms were tolerable; they dismissed it, simply waiting for the aliment to heal itself. Today there is mounting evidence that inflammation can make a significant impact on one’s health.

According to a report published last year in the Journal of the American Medical Association, doctors are suspecting—and gathering an alarming amount of proof— that inflammation, whether triggered by an infection or another health condition, can damage the walls of heart arteries, making them prone to fat buildups that can lead to heart attacks.

Inflammation can result from arthritis, allergies, asthma, stress or even minor sinus or wound infections. It is much more serious than we thought; even a small amount left for a long period of time can have severe consequences and lead to heart disease. Americans are becoming smarter consumers, taking charge of their health by educating themselves and taking preventative measures such as changing their lifestyles by incorporating proper diet and exercise and increasing their intake of antioxidants through diet or supplementation, such as Pycnogenol® (pic-noj-en-all).

Pycnogenol, French maritime pine bark extract, is a super antioxidant that helps reduce inflammation by neutralizing free radicals released by inflammation. More than decade of research (90 studies in all) has shown that one of its primary benefits is its increasingly important role in the prevention of risk factors such as inflammation and high blood pressure that may cause heart disease. The following describes research findings on Pycnogenol’s ability to counteract inflammation in some of the most common health conditions. The majority of these studies involve the cardiovascular system providing solid evidence that this antioxidant is the most powerful in reducing inflammation, strengthening the vascular system, lowering high blood pressure and cholesterol and fighting the effects of smoking and other environmental factors on the heart.

Hypertension
Hypertension is the major U.S. cause of premature death due to heart disease. The elevated blood pressure causes physical stress to blood cells and vessel walls which in turn initiates an inflammatory process, leading to an increased risk of heart disease. Dr. Ronald Watson of the University of Arizona has researched the health benefits of Pycnogenol for his patients for years. He published the results of a clinical study demonstrating that Pycnogenol reduces blood pressure in mild hypertensives.

Dr. Watson also discovered that Pycnogenol inhibits platelet aggregation induced by cigarette smoking, without the adverse effect on bleeding time that characterizes aspirin use. This means that it helps reduce the risk of blood clots that can restrict blood flow through the blood vessels, leading to inflammation and clotting. Pycnogenol’s bioflavonoids repressed smoke-activated platelets, reducing another risk factor of hypertension. Further evidence of its effectiveness as an antioxidant is the patent awarded to Pycnogenol for its ability to scavenge harmful free radicals. The most recent correlation between Pycnogenol and heart health is a clinical study on cholesterol reduction. Results of the study found that Pycnogenol significantly reduced the LDL-cholesterol levels (often referred to as “bad” cholesterol) in the blood, while the HDL-cholesterol (the “good” cholesterol) was elevated. LDL-cholesterol is the cause for deposits of fatty streaks on artery walls which in turn get inflamed, the onset of atherosclerosis. Once again, this powerful antioxidant reduced another risk factor of heart disease.

Asthma
Asthma is believed to result from inflammatory processes of the bronchi, causing them to constrict and swell, aggravating airflow. In many patients this can cause an obstruction of the airways. A clinical study by Dr. Watson showed that after taking Pycnogenol, asthmatics noted improvement of their breathing ability. This was a result of Pycnogenol’s capability to reduce significantly inflammatory mediators.

Allergies and Hay Fever
Allergies are inappropriate responses of the body’s immune system toward substances it mistakenly perceives as harmful. Allergens causing these reactions are most commonly pollen, dust, certain metals, animal hair or food additives. When an allergic person comes into contact with an allergen, a particular subset of the immune system release the histamine. During this immediate reaction, histamine triggers symptoms common to allergies: sneezing, nasal congestion, coughing, skin rashes and swelling. Inflammatory mediators may cause these symptoms to persist. According to several clinical studies, Pycnogenol inhibits the release of histamine, thus preventing the immediate reaction toward a challenge with an antigen; because it is an anti-inflammatory, it inhibits production of pro-flammatory mediators. It relieves the swelling, reduces hives and helps make breathing easier.

What makes Pycnogenol French maritime pine bark extract unique in the vast sea of dietary supplements, multi-vitamins and natural products lining store shelves in the fight against inflammation is that it is an evidence-based antioxidant. As discussed earlier, millions of dollars have been spent in extensive research and clinical evidence has been conducted to assure the safety and efficacy of Pycnogenol as a dietary supplement. So, continue to stay healthy and fight inflammation in some of the most common health conditions that can surface daily by taking nature’s super antioxidant, Pycnogenol. To learn more about Pycnogenol research and its fight against inflammation, visit www.pycnogenol.com TH

Frank Schönlau, Ph.D. is director of scientific communication at Horphag Research.
 
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